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Target
Cytochrome P450 2B1
Ligand
BDBM50404907
Substrate
n/a
Meas. Tech.
ChEMBL_35524 (CHEMBL644757)
IC50
26915.35±n/a nM
Citation
 Murray, M; Ryan, AJ; Little, PJ Inhibition of rat hepatic microsomal aminopyrine N-demethylase activity by benzimidazole derivatives. Quantitative structure-activity relationships. J Med Chem 25:887-92 (1982) [PubMed]  Article 
Target
Name:
Cytochrome P450 2B1
Synonyms:
CP2B1_RAT | Cyp2b-1 | Cyp2b1
Type:
PROTEIN
Mol. Mass.:
55940.51
Organism:
Rattus norvegicus
Description:
ChEMBL_774167
Residue:
491
Sequence:
MEPTILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR
  
Inhibitor
Name:
BDBM50404907
Synonyms:
CHEMBL172114
Type:
Small organic molecule
Emp. Form.:
C14H10ClN3O
Mol. Mass.:
271.702
SMILES:
Clc1cc(NC(=O)c2ccccc2)c2[nH]cnc2c1
Structure:
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