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TargetInosine-5'-monophosphate dehydrogenase
LigandBDBM50405116
Substrate/Competitorn/a
Meas. Tech.ChEMBL_89670
IC50 56000±n/a nM
Citation Wong, CGMeyer, RB Inhibitors of inosinic acid dehydrogenase. 2-Substituted inosinic acids. J Med Chem27:429-32 (1984) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Inosine-5'-monophosphate dehydrogenase
Name:Inosine-5'-monophosphate dehydrogenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:52020.85
Organism:Escherichia coli (strain K12)
Description:ChEMBL_89670
Residue:488
Sequence:
MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIA
LAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAG
YPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRV
EKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAA
GVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIG
PGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMV
GSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR
VAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKE
SPNYRLGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50405116
NameBDBM50405116
Synonyms:CHEMBL612226
TypeSmall organic molecule
Emp. Form.C17H18N5O10PS
Mol. Mass.515.391
SMILESO[C@H]1[C@H](CO[P+](O)(O)[O-])OC([C@H]1O)n1cnc2c1nc(SCc1ccc(cc1)[N+]([O-])=O)[nH]c2=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a