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TargetInosine-5'-monophosphate dehydrogenase
LigandBDBM50405125
Substrate/Competitorn/a
Meas. Tech.ChEMBL_89670
IC50>1000000±n/a nM
Citation Wong, CGMeyer, RB Inhibitors of inosinic acid dehydrogenase. 2-Substituted inosinic acids. J Med Chem27:429-32 (1984) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Inosine-5'-monophosphate dehydrogenase
Name:Inosine-5'-monophosphate dehydrogenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:52020.85
Organism:Escherichia coli (strain K12)
Description:ChEMBL_89670
Residue:488
Sequence:
MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIA
LAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAG
YPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRV
EKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAA
GVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIG
PGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMV
GSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR
VAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKE
SPNYRLGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50405125
NameBDBM50405125
Synonyms:CHEMBL611911
TypeSmall organic molecule
Emp. Form.C15H16N5O8P
Mol. Mass.425.29
SMILESO[C@H]1[C@H](COP(O)(O)=O)OC([C@H]1O)n1cnc2c1nc([nH]c2=O)-c1cccnc1 |r|
Structure
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n/a