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Target
Lutropin-choriogonadotropic hormone receptor
Ligand
BDBM50405775
Substrate
n/a
Meas. Tech.
ChEMBL_100146 (CHEMBL712503)
Ki
17±n/a nM
Citation
 Haviv, F; Palabrica, CA; Bush, EN; Diaz, G; Johnson, ES; Love, S; Greer, J Active reduced-size hexapeptide analogues of luteinizing hormone-releasing hormone. J Med Chem 32:2340-4 (1989) [PubMed]  Article 
Target
Name:
Lutropin-choriogonadotropic hormone receptor
Synonyms:
LH/CG-R | LSH-R | LSHR_RAT | Lhcgr | Luteinizing hormone receptor | Luteinizing hormone/Choriogonadotropin receptor | Lutropin-choriogonadotropic hormone receptor
Type:
PROTEIN
Mol. Mass.:
78049.26
Organism:
Rattus norvegicus
Description:
ChEMBL_97289
Residue:
700
Sequence:
MGRRVPALRQLLVLAVLLLKPSQLQSRELSGSRCPEPCDCAPDGALRCPGPRAGLARLSLTYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLLNLSELLIQNTKNLLYIEPGAFTNLPRLKYLSICNTGIRTLPDVTKISSSEFNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMHSGAFQGATGPSILDISSTKLQALPSHGLESIQTLIALSSYSLKTLPSKEKFTSLLVATLTYPSHCCAFRNLPKKEQNFSFSIFENFSKQCESTVRKADNETLYSAIFEENELSGWDYDYGFCSPKTLQCAPEPDAFNPCEDIMGYAFLRVLIWLINILAIFGNLTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCGAAGFFTVFASELSVYTLTVITLERWHTITYAVQLDQKLRLRHAIPIMLGGWLFSTLIATMPLVGISNYMKVSICLPMDVESTLSQVYILSILILNVVAFVVICACYIRIYFAVQNPELTAPNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFLLLLSRFGCCKRRAELYRRKEFSAYTSNCKNGFPGASKPSQATLKLSTVHCQQPIPPRALTH
  
Inhibitor
Name:
BDBM50405775
Synonyms:
CHEMBL2369806
Type:
Small organic molecule
Emp. Form.:
C51H69N11O9
Mol. Mass.:
980.1619
SMILES:
CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12 |wU:5.4,42.44,31.32,23.24,wD:54.57,12.13,(27.82,-9.83,;26.35,-9.43,;25.96,-7.93,;24.48,-7.54,;23.37,-8.61,;24.07,-6.04,;25.05,-4.85,;24.22,-3.56,;22.72,-3.95,;22.63,-5.49,;21.31,-4.72,;21.33,-3.18,;19.99,-5.49,;19.96,-7.03,;21.28,-7.81,;21.27,-9.35,;22.6,-10.14,;22.56,-11.68,;21.24,-12.43,;23.9,-12.46,;18.64,-4.69,;17.3,-5.49,;17.33,-7.03,;15.98,-4.73,;15.95,-3.19,;17.27,-2.41,;17.27,-.87,;18.62,-3.15,;14.64,-5.5,;13.29,-4.75,;13.29,-3.21,;11.98,-5.53,;11.98,-7.07,;13.32,-7.83,;14.63,-7.04,;15.95,-7.8,;15.99,-9.34,;14.66,-10.12,;13.32,-9.35,;10.63,-4.76,;9.3,-5.55,;9.31,-7.09,;7.93,-4.79,;7.93,-3.24,;9.27,-2.45,;9.25,-.91,;10.6,-.14,;11.93,-.9,;13.26,-.11,;11.94,-2.44,;10.62,-3.22,;6.62,-5.56,;5.27,-4.81,;5.27,-3.27,;3.96,-5.59,;3.96,-7.13,;5.3,-7.89,;2.61,-4.82,;1.26,-5.61,;1.29,-7.16,;-.06,-4.85,;-.09,-3.32,;-1.41,-2.55,;-2.84,-3.19,;-3.87,-2.05,;-3.1,-.71,;-3.59,.76,;-2.57,1.91,;-1.06,1.6,;-.57,.15,;-1.59,-1.03,)|
Structure:
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