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Target
Protein Tat
Ligand
BDBM50407476
Substrate
n/a
Meas. Tech.
ChEMBL_199318 (CHEMBL805260)
IC50
33500±n/a nM
Citation
 Michne, WF; Schroeder, JD; Bailey, TR; Neumann, HC; Cooke, D; Young, DC; Hughes, JV; Kingsley, SD; Ryan, KA; Putz, HS Keto/enol epoxy steroids as HIV-1 Tat inhibitors: structure-activity relationships and pharmacophore localization. J Med Chem 38:3197-206 (1995) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat
Type:
PROTEIN
Mol. Mass.:
9771.75
Organism:
Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1)
Description:
ChEMBL_199318
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
  
Inhibitor
Name:
BDBM50407476
Synonyms:
CHEMBL325765
Type:
Small organic molecule
Emp. Form.:
C19H24ClNO4
Mol. Mass.:
365.851
SMILES:
COc1ccc(NC(=O)C2C[C@]3(C)CCCC[C@@]3(O)[C@@H](Cl)C2=O)cc1
Structure:
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