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Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50407773
Substrate
n/a
Meas. Tech.
ChEMBL_1953 (CHEMBL617560)
IC50
2570.4±n/a nM
Citation
 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines. J Med Chem 39:2068-80 (1996) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor
Type:
PROTEIN
Mol. Mass.:
32680.56
Organism:
Sus scrofa
Description:
ChEMBL_1963
Residue:
291
Sequence:
AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
  
Inhibitor
Name:
BDBM50407773
Synonyms:
CHEMBL65736
Type:
Small organic molecule
Emp. Form.:
C17H20N4S
Mol. Mass.:
312.432
SMILES:
C(C1CC1)N1CCN(CC1)c1nc2ccsc2n2cccc12
Structure:
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