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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50407767
Substrate
n/a
Meas. Tech.
ChEMBL_2255 (CHEMBL873476)
IC50
1288.25±n/a nM
Citation
 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines. J Med Chem 39:2068-80 (1996) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT2A | 5HT2A_BOVIN | 5HTR2A | HTR2A | Serotonin 2a (5-HT2a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52578.24
Organism:
BOVINE
Description:
5-HT2A HTR2A BOVINE::Q75Z89
Residue:
470
Sequence:
MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV
  
Inhibitor
Name:
BDBM50407767
Synonyms:
CHEMBL65974
Type:
Small organic molecule
Emp. Form.:
C14H16N4S
Mol. Mass.:
272.369
SMILES:
CN1CCN(CC1)c1nc2ccsc2n2cccc12
Structure:
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