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Target
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligand
BDBM50191588
Substrate
n/a
Meas. Tech.
ChEMBL_376967 (CHEMBL870329)
IC50
2±n/a nM
Citation
 Bolgunas, S; Clark, DA; Hanna, WS; Mauvais, PA; Pember, SO Potent inhibitors of the Qi site of the mitochondrial respiration complex III. J Med Chem 49:4762-6 (2006) [PubMed]  Article 
Target
Name:
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Synonyms:
Ip | Iron-sulfur subunit of complex II | SDH2 | SDHB_ZYMTR
Type:
PROTEIN
Mol. Mass.:
33680.57
Organism:
Septoria tritici
Description:
ChEMBL_376968
Residue:
297
Sequence:
MALRLATRRFAPIAFRRGMATTIEHTKEPISATAEALSASRPPIKETKTSTVKEPQMDADAKTKTFHIYRWNPDQPTDKPRMQSYTLDLNKTGPMMLDALIRIKNEVDPTLTFRRSCREGICGSCAMNIDGVNTLACLCRIPTDTAKETRIYPLPHTYVVKDLVPDMTQFYKQYKSIKPYLQRDTAPPDGKENRQSVADRKKLDGLYECILCACCSTSCPSYWWNSEEYLGPAVLLQSYRWINDSRDEKTAQRKDALNNSMSLYRCHTILNCSRTCPKGLNPALAIAEIKKSMAFTG
  
Inhibitor
Name:
BDBM50191588
Synonyms:
(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate | Antimycin A1 | Antipiricullin | CHEMBL211501 | Fintrol | Virosin | antimycin A | antimycin A1b
Type:
Small organic molecule
Emp. Form.:
C28H40N2O9
Mol. Mass.:
548.6252
SMILES:
CCCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O |r|
Structure:
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