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Target
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligand
BDBM50411098
Substrate
n/a
Meas. Tech.
ChEMBL_376967 (CHEMBL870329)
IC50
127±n/a nM
Citation
 Bolgunas, S; Clark, DA; Hanna, WS; Mauvais, PA; Pember, SO Potent inhibitors of the Qi site of the mitochondrial respiration complex III. J Med Chem 49:4762-6 (2006) [PubMed]  Article 
Target
Name:
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Synonyms:
Ip | Iron-sulfur subunit of complex II | SDH2 | SDHB_ZYMTR
Type:
PROTEIN
Mol. Mass.:
33680.57
Organism:
Septoria tritici
Description:
ChEMBL_376968
Residue:
297
Sequence:
MALRLATRRFAPIAFRRGMATTIEHTKEPISATAEALSASRPPIKETKTSTVKEPQMDADAKTKTFHIYRWNPDQPTDKPRMQSYTLDLNKTGPMMLDALIRIKNEVDPTLTFRRSCREGICGSCAMNIDGVNTLACLCRIPTDTAKETRIYPLPHTYVVKDLVPDMTQFYKQYKSIKPYLQRDTAPPDGKENRQSVADRKKLDGLYECILCACCSTSCPSYWWNSEEYLGPAVLLQSYRWINDSRDEKTAQRKDALNNSMSLYRCHTILNCSRTCPKGLNPALAIAEIKKSMAFTG
  
Inhibitor
Name:
BDBM50411098
Synonyms:
CHEMBL377384
Type:
Small organic molecule
Emp. Form.:
C20H15N3O3
Mol. Mass.:
345.3514
SMILES:
Oc1c(ccc2c[nH]nc12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Structure:
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