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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50378564
Substrate
n/a
Meas. Tech.
ChEMBL_417161 (CHEMBL909462)
IC50
1.7±n/a nM
Citation
 Novaroli, L; Daina, A; Favre, E; Bravo, J; Carotti, A; Leonetti, F; Catto, M; Carrupt, PA; Reist, M Impact of species-dependent differences on screening, design, and development of MAO B inhibitors. J Med Chem 49:6264-72 (2006) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50378564
Synonyms:
CHEMBL145781
Type:
Small organic molecule
Emp. Form.:
C16H12O3
Mol. Mass.:
252.2647
SMILES:
O=c1ccc2ccc(OCc3ccccc3)cc2o1
Structure:
Search PDB for entries with ligand similarity: