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Target2,3-dihydroxybenzoate-AMP ligase
LigandBDBM50411235
Substrate/Competitorn/a
Meas. Tech.ChEMBL_423930
Ki 3.5±n/a nM
Citation Somu, RVWilson, DJBennett, EMBoshoff, HICelia, LBeck, BJBarry, CEAldrich, CC Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain. J Med Chem49:7623-35 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
2,3-dihydroxybenzoate-AMP ligase
Name:2,3-dihydroxybenzoate-AMP ligase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:59275.32
Organism:Mycobacterium tuberculosis
Description:ChEMBL_423930
Residue:565
Sequence:
MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA
DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA
IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP
GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL
CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA
LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL
NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER
DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS
AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPI
GKIDKRAIVRQLGIATGPVTTQRCH
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  Blast E-value cutoff:
BDBM50411235
NameBDBM50411235
Synonyms:CHEMBL612022
TypeSmall organic molecule
Emp. Form.C17H18N6O7S
Mol. Mass.450.426
SMILESNc1ncnc2ncn(C3CC(O)C(COS(=O)(=O)NC(=O)c4ccccc4O)O3)c12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a