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TargetAlpha-2B adrenergic receptor
LigandBDBM50412258
Substrate/Competitorn/a
Meas. Tech.ChEMBL_487923
EC50 200±n/a nM
Citation Gentili, FCardinaletti, CVesprini, CCarrieri, AGhelfi, FFarande, AGiannella, MPiergentili, AQuaglia, WLaurila, JMHuhtinen, AScheinin, MPigini, M Alpha2-adrenoreceptors profile modulation. 4. From antagonist to agonist behavior. J Med Chem51:4289-99 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-2B adrenergic receptor
Name:Alpha-2B adrenergic receptor
Synonyms:ADRA2B | ADRA2L1 | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:Enzyme
Mol. Mass.:49579.89
Organism:Homo sapiens (Human)
Description:P18089
Residue:450
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
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  Blast E-value cutoff:
BDBM50412258
NameBDBM50412258
Synonyms:CHEMBL451229
TypeSmall organic molecule
Emp. Form.C17H24N2O
Mol. Mass.272.3853
SMILESCC(Oc1ccccc1C1CCCCC1)C1=NCCN1 |t:17|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a