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Target
Cytochrome P450 2A5
Ligand
BDBM50159254
Substrate
n/a
Meas. Tech.
ChEMBL_572014 (CHEMBL1023676)
IC50
13996±n/a nM
Citation
 Roy, K; Roy, PP Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques. Eur J Med Chem 44:1941-51 (2009) [PubMed]  Article 
Target
Name:
Cytochrome P450 2A5
Synonyms:
CP2A5_MOUSE | Cyp2a-5 | Cyp2a5
Type:
PROTEIN
Mol. Mass.:
56752.73
Organism:
Mus musculus
Description:
ChEMBL_572014
Residue:
494
Sequence:
MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNFLQLNTEQMYNSLMKISQRYGPVFTIYLGPRRIVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVVFSSGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKNDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQAPQDIDVSPRLVGFATIPPTYTMSFLSR
  
Inhibitor
Name:
BDBM50159254
Synonyms:
3,4-Dihydro-2H-naphthalen-1-one | 3,4-dihydronaphthalen-1(2H)-one | CHEMBL193373
Type:
Small organic molecule
Emp. Form.:
C10H10O
Mol. Mass.:
146.1858
SMILES:
O=C1CCCc2ccccc12
Structure:
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