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Target
Aldehyde dehydrogenase, mitochondrial
Ligand
BDBM50414919
Substrate
n/a
Meas. Tech.
ChEMBL_592877 (CHEMBL1046622)
IC50
15848.93±n/a nM
Citation
 Kapanda, CN; Muccioli, GG; Labar, G; Poupaert, JH; Lambert, DM Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors. J Med Chem 52:7310-4 (2009) [PubMed]  Article 
Target
Name:
Aldehyde dehydrogenase, mitochondrial
Synonyms:
ALDH2_RAT | Aldehyde dehydrogenase | Aldh2
Type:
PROTEIN
Mol. Mass.:
56489.77
Organism:
Rattus norvegicus
Description:
ChEMBL_592877
Residue:
519
Sequence:
MLRAALSTARRGPRLSRLLSAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
  
Inhibitor
Name:
BDBM50414919
Synonyms:
CHEMBL571699
Type:
Small organic molecule
Emp. Form.:
C12H22N4S4
Mol. Mass.:
350.59
SMILES:
CN1CCN(CC1)C(=S)SSC(=S)N1CCN(C)CC1
Structure:
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