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Target
Fatty-acid amide hydrolase 1
Ligand
BDBM50132713
Substrate
n/a
Meas. Tech.
ChEMBL_592876 (CHEMBL1046621)
IC50
0.331±n/a nM
Citation
 Kapanda, CN; Muccioli, GG; Labar, G; Poupaert, JH; Lambert, DM Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors. J Med Chem 52:7310-4 (2009) [PubMed]  Article 
Target
Name:
Fatty-acid amide hydrolase 1
Synonyms:
Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1
Type:
Protein
Mol. Mass.:
63071.19
Organism:
Homo sapiens (Human)
Description:
O00519
Residue:
579
Sequence:
MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAFLVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALDLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
  
Inhibitor
Name:
BDBM50132713
Synonyms:
Arachidonic acid derivative | CHEMBL113262 | Methyl arachidonoyl fluorophophonate | methyl ((5Z,8Z,11Z,14Z)-2-Icosa-5,8,11,14-tetraenyl)phosphonofluoridoate | methyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenylphosphonofluoridate | methyl -icosa-5,8,11,14-tetraenylphosphonofluoridate | methyl(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenylphosphonofluoridate | methylarachidonyl fluorophosphonate
Type:
Small organic molecule
Emp. Form.:
C21H36FO2P
Mol. Mass.:
370.4815
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCP(F)(=O)OC
Structure:
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