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Target
ATP synthase subunit c
Ligand
BDBM50333125
Substrate
n/a
Meas. Tech.
ChEMBL_653029 (CHEMBL1226232)
IC50
2.5±n/a nM
Citation
 Koul, A; Dendouga, N; Vergauwen, K; Molenberghs, B; Vranckx, L; Willebrords, R; Ristic, Z; Lill, H; Dorange, I; Guillemont, J; Bald, D; Andries, K Diarylquinolines target subunit c of mycobacterial ATP synthase. Nat Chem Biol 3:323-4 (2007) [PubMed]  Article 
Target
Name:
ATP synthase subunit c
Synonyms:
Putative uncharacterized protein atpE | Subunit c of ATP synthase
Type:
PROTEIN
Mol. Mass.:
8592.94
Organism:
Mycobacterium smegmatis
Description:
ChEMBL_653029
Residue:
86
Sequence:
MDLDPNAIITAGALIGGGLIMGGGAIGAGIGDGIAGNALISGIARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPGLQ
  
Inhibitor
Name:
BDBM50333125
Synonyms:
(1R,2S)-1-(6-bromoquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol | CHEMBL1631683
Type:
Small organic molecule
Emp. Form.:
C31H29BrN2O
Mol. Mass.:
525.479
SMILES:
CN(C)CC[C@](O)([C@H](c1ccccc1)c1cnc2ccc(Br)cc2c1)c1cccc2ccccc12 |r|
Structure:
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