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Target
Melatonin receptor type 1B
Ligand
BDBM50416696
Substrate
n/a
Meas. Tech.
ChEMBL_652046 (CHEMBL1227856)
Ki
263.03±n/a nM
Citation
 Carocci, A; Catalano, A; Lovece, A; Lentini, G; Duranti, A; Lucini, V; Pannacci, M; Scaglione, F; Franchini, C Design, synthesis, and pharmacological effects of structurally simple ligands for MT(1) and MT(2) melatonin receptors. Bioorg Med Chem 18:6496-511 (2010) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50416696
Synonyms:
CHEMBL1223281
Type:
Small organic molecule
Emp. Form.:
C12H17NO2S
Mol. Mass.:
239.334
SMILES:
COc1cccc(SC[C@H](C)NC(C)=O)c1 |r|
Structure:
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