Reaction Details Report a problem with these data
Target
Cytochrome P450 2B4
Ligand
BDBM50027789
Substrate
n/a
Meas. Tech.
ChEMBL_774152 (CHEMBL1908247)
Ki
2000000±n/a nM
Citation
 Fontana, E; Dansette, PM; Poli, SM Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab 6:413-54 (2005) [PubMed]  Article 
Target
Name:
Cytochrome P450 2B4
Synonyms:
CP2B4_RABIT | CYP2B4 | CYPIIB4 | Cytochrome P450 LM2 | Cytochrome P450 isozyme 2 | Cytochrome P450 type B0 | Cytochrome P450 type B1
Type:
PROTEIN
Mol. Mass.:
55725.83
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_774153
Residue:
491
Sequence:
MEFSLLLLLAFLAGLLLLLFRGHPKAHGRLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFPGFLKHFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLAR
  
Inhibitor
Name:
BDBM50027789
Synonyms:
CHEMBL1908217
Type:
Small organic molecule
Emp. Form.:
C6H4N2O2S2
Mol. Mass.:
200.238
SMILES:
COC(=O)c1csc2snnc12
Structure:
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