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Target
Soluble acetylcholine receptor
Ligand
BDBM50419732
Substrate
n/a
Meas. Tech.
ChEMBL_801487 (CHEMBL1948414)
Ki
31.62±n/a nM
Citation
 Edink, E; Akdemir, A; Jansen, C; van Elk, R; Zuiderveld, O; de Kanter, FJ; van Muijlwijk-Koezen, JE; Smit, AB; Leurs, R; de Esch, IJ Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein. Bioorg Med Chem Lett 22:1448-54 (2012) [PubMed]  Article 
Target
Name:
Soluble acetylcholine receptor
Synonyms:
Acetylcholine Binding protein | Soluble acetylcholine receptor
Type:
n/a
Mol. Mass.:
26560.08
Organism:
Aplysia Californica
Description:
Q8WSF8
Residue:
236
Sequence:
MLVSVYLALLVACVGQAHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAGNGFFRNLFD
  
Inhibitor
Name:
BDBM50419732
Synonyms:
CHEMBL1947053
Type:
Small organic molecule
Emp. Form.:
C22H25NO2
Mol. Mass.:
335.4394
SMILES:
O=C(O[C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1 |r,THB:11:10:4.3.9:7.6|
Structure:
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