Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 11
Ligand
BDBM85245
Substrate
n/a
Meas. Tech.
ChEMBL_836111 (CHEMBL2077547)
Ki
107800±n/a nM
Citation
 Babu, E; Takeda, M; Narikawa, S; Kobayashi, Y; Enomoto, A; Tojo, A; Cha, SH; Sekine, T; Sakthisekaran, D; Endou, H Role of human organic anion transporter 4 in the transport of ochratoxin A. Biochim Biophys Acta 1590:64-75 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 11
Synonyms:
OAT4 | Organic anion transporter 4 | S22AB_HUMAN | SLC22A11
Type:
PROTEIN
Mol. Mass.:
59982.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_838708
Residue:
550
Sequence:
MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
  
Inhibitor
Name:
BDBM85245
Synonyms:
CAS_36322-90-4 | NSC_4856 | Piroxicam
Type:
Small organic molecule
Emp. Form.:
C15H13N3O4S
Mol. Mass.:
331.346
SMILES:
CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |t:12|
Structure:
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