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Target
Solute carrier family 22 member 6
Ligand
BDBM85245
Substrate
n/a
Meas. Tech.
ChEMBL_838479 (CHEMBL2076050)
Ki
52000±n/a nM
Citation
 Apiwattanakul, N; Sekine, T; Chairoungdua, A; Kanai, Y; Nakajima, N; Sophasan, S; Endou, H Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol 55:847-54 (1999) [PubMed] 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1
Type:
PROTEIN
Mol. Mass.:
60784.17
Organism:
Rattus norvegicus
Description:
ChEMBL_838479
Residue:
551
Sequence:
MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKDGGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMPLQASTQEKNGL
  
Inhibitor
Name:
BDBM85245
Synonyms:
CAS_36322-90-4 | NSC_4856 | Piroxicam
Type:
Small organic molecule
Emp. Form.:
C15H13N3O4S
Mol. Mass.:
331.346
SMILES:
CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |t:12|
Structure:
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