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Target
Somatostatin receptor type 1
Ligand
BDBM50423335
Substrate
n/a
Meas. Tech.
ChEMBL_456104 (CHEMBL888113)
Kd
3.6±n/a nM
Citation
 Hurth, K; Enz, A; Floersheim, P; Gentsch, C; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Sorg, D; Swoboda, R; Vassout, A; Troxler, T SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists. Bioorg Med Chem Lett 17:3988-91 (2007) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS1R | SSR1_RAT | Somatostatin receptor | Somatostatin receptor type 1 | Sstr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42752.93
Organism:
RAT
Description:
SOMATOSTATIN SST1 SSTR1 RAT::P28646
Residue:
391
Sequence:
MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL
  
Inhibitor
Name:
BDBM50423335
Synonyms:
CHEMBL250921
Type:
Small organic molecule
Emp. Form.:
C26H31N5O3
Mol. Mass.:
461.556
SMILES:
COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cccc4nonc34)Cc12
Structure:
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