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Target
NAD-dependent protein deacetylase
Ligand
BDBM50424422
Substrate
n/a
Meas. Tech.
ChEMBL_936768 (CHEMBL2320160)
IC50
5700±n/a nM
Citation
 Zheng, W Sirtuins as emerging anti-parasitic targets. Eur J Med Chem 59:132-40 (2013) [PubMed]  Article 
Target
Name:
NAD-dependent protein deacetylase
Synonyms:
Putative silent information regulator 2 | SIR2-like protein | SIR2RP1
Type:
PROTEIN
Mol. Mass.:
40532.98
Organism:
Leishmania infantum
Description:
ChEMBL_936768
Residue:
373
Sequence:
MTASPRAPHQEHVLGEPTLEGLAHYIREKNVRRILVLVGAGASVAAGIPDFRSPDTGIYANLGKYNLEDPTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSVPRVVMNRERVGGLLFRFPDDPLNTVHEDAVAKEGRSSSSQSRSPSASPRREEGGTEDSPSSPNEEVEEASTSSSSDGYGQYGDYHAHPDVCRDVLFRGDCQENVVTLAEYLGLSEALAKRMRLSDAAPATAQRAPNET
  
Inhibitor
Name:
BDBM50424422
Synonyms:
BNIPDanon | CHEMBL228002
Type:
Small organic molecule
Emp. Form.:
C39H44N4O4
Mol. Mass.:
632.7911
SMILES:
O=C1N(CCCNCCCCCCCCCNCCCN2C(=O)c3cccc4cccc(C2=O)c34)C(=O)c2cccc3cccc1c23
Structure:
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