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Target
Casein kinase I isoform alpha
Ligand
BDBM50426317
Substrate
n/a
Meas. Tech.
ChEMBL_939731 (CHEMBL2329084)
IC50
>10000±n/a nM
Citation
 Myrianthopoulos, V; Kritsanida, M; Gaboriaud-Kolar, N; Magiatis, P; Ferandin, Y; Durieu, E; Lozach, O; Cappel, D; Soundararajan, M; Filippakopoulos, P; Sherman, W; Knapp, S; Meijer, L; Mikros, E; Skaltsounis, AL Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases. ACS Med Chem Lett 4:22-26 (2013) [PubMed]  Article 
Target
Name:
Casein kinase I isoform alpha
Synonyms:
CK1 | CKI-alpha | CSNK1A1 | KC1A_PIG
Type:
PROTEIN
Mol. Mass.:
14639.55
Organism:
Sus scrofa
Description:
ChEMBL_939731
Residue:
125
Sequence:
GEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY
  
Inhibitor
Name:
BDBM50426317
Synonyms:
CHEMBL2321960
Type:
Small organic molecule
Emp. Form.:
C18H12BrN3O4
Mol. Mass.:
414.21
SMILES:
COC(=O)c1ccc2c(N=O)c([nH]c2c1)C1C(=O)Nc2c1cccc2Br
Structure:
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