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TargetAlkaline ceramidase 2
LigandBDBM50392473
Substrate/Competitorn/a
Meas. Tech.ChEMBL_947532
IC50 1000±n/a nM
Citation Bhabak, KPKleuser, BHuwiler, AArenz, C Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues. Bioorg Med Chem21:874-82 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alkaline ceramidase 2
Name:Alkaline ceramidase 2
Synonyms:ACER2 | ASAH3L | Acylsphingosine deacylase 3-like | AlkCDase 2 | Alkaline CDase 2 | N-acylsphingosine amidohydrolase 3-like | haCER2
Type:PROTEIN
Mol. Mass.:31312.92
Organism:Homo sapiens (Human)
Description:ChEMBL_947532
Residue:275
Sequence:
MGAPHWWDQLQAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCF
NSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRN
DRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLF
SGLWWTLALFCWISDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPE
QGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50392473
NameBDBM50392473
Synonyms:CHEMBL429926
TypeSmall organic molecule
Emp. Form.C23H39NO2
Mol. Mass.361.5613
SMILESCCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a