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Target
Casein kinase I isoform alpha
Ligand
BDBM50432004
Substrate
n/a
Meas. Tech.
ChEMBL_954191 (CHEMBL2351706)
IC50
>10000±n/a nM
Citation
 Elagawany, M; Ibrahim, MA; Ali Ahmed, HE; El-Etrawy, ASh; Ghiaty, A; Abdel-Samii, ZK; El-Feky, SA; Bajorath, J Design, synthesis, and molecular modelling of pyridazinone and phthalazinone derivatives as protein kinases inhibitors. Bioorg Med Chem Lett 23:2007-13 (2013) [PubMed]  Article 
Target
Name:
Casein kinase I isoform alpha
Synonyms:
CK1 | CKI-alpha | CSNK1A1 | KC1A_PIG
Type:
PROTEIN
Mol. Mass.:
14639.55
Organism:
Sus scrofa
Description:
ChEMBL_939731
Residue:
125
Sequence:
GEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY
  
Inhibitor
Name:
BDBM50432004
Synonyms:
CHEMBL2348739
Type:
Small organic molecule
Emp. Form.:
C24H18ClN3O2
Mol. Mass.:
415.872
SMILES:
Clc1nnc(N(C(=O)Cc2ccccc2)C(=O)Cc2ccccc2)c2ccccc12
Structure:
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