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Target
N-formyl peptide receptor 3
Ligand
BDBM50435891
Substrate
n/a
Meas. Tech.
ChEMBL_963919 (CHEMBL2393754)
EC50
>50000±n/a nM
Citation
 Giovannoni, MP; Schepetkin, IA; Cilibrizzi, A; Crocetti, L; Khlebnikov, AI; Dahlgren, C; Graziano, A; Dal Piaz, V; Kirpotina, LN; Zerbinati, S; Vergelli, C; Quinn, MT Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. Eur J Med Chem 64:512-28 (2013) [PubMed]  Article 
Target
Name:
N-formyl peptide receptor 3
Synonyms:
FML2_HUMAN | FPR3 | FPR3_HUMAN | FPRH1 | FPRL2
Type:
PROTEIN
Mol. Mass.:
39971.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_580003
Residue:
353
Sequence:
METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
  
Inhibitor
Name:
BDBM50435891
Synonyms:
CHEMBL2391452
Type:
Small organic molecule
Emp. Form.:
C20H18BrN3O3
Mol. Mass.:
428.279
SMILES:
COc1ccc(cc1)-c1cc(C)nn(CC(=O)Nc2ccc(Br)cc2)c1=O
Structure:
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