Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM50404862
Substrate
n/a
Meas. Tech.
ChEMBL_964310 (CHEMBL2395572)
EC50
4840±n/a nM
Citation
 Funke, M; Thimm, D; Schiedel, AC; Müller, CE 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35. J Med Chem 56:5182-97 (2013) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
GPR35_MOUSE | Gpr35 | KYNA receptor | Kynurenic acid receptor
Type:
PROTEIN
Mol. Mass.:
34163.11
Organism:
Mus musculus
Description:
ChEMBL_107606
Residue:
307
Sequence:
MNSTTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMHQWTETRIYMTNLAVADLCLLCSLPFVLYSLKYSSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGGFCFSSQTRRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLNTCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATSSNTPHKSQDSQILSLT
  
Inhibitor
Name:
BDBM50404862
Synonyms:
CROMOLYN SODIUM | Crolom | Cromoglicic Acid | Cromoglycic Acid | Cromolyn
Type:
Small organic molecule
Emp. Form.:
C23H14O11
Mol. Mass.:
466.3518
SMILES:
OC(COc1cccc2oc(cc(=O)c12)C([O-])=O)COc1cccc2oc(cc(=O)c12)C([O-])=O
Structure:
Search PDB for entries with ligand similarity: