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TargetAcetylpolyamine amidohydrolase (APAH)
LigandBDBM50438388
Substrate/Competitorn/a
Meas. Tech.ChEMBL_975718
IC50 380000±n/a nM
Citation Decroos, CBowman, CMChristianson, DW Synthesis and evaluation of N8-acetylspermidine analogues as inhibitors of bacterial acetylpolyamine amidohydrolase. Bioorg Med Chem21:4530-40 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylpolyamine amidohydrolase (APAH)
Name:Acetylpolyamine amidohydrolase (APAH)
Synonyms:Acetylpolyamine aminohydrolase
Type:Protein
Mol. Mass.:36324.64
Organism:Mycoplana ramosa (Gram-negative bacterium)
Description:n/a
Residue:341
Sequence:
MRVIFSEDHKLRNAKTELYGGELVPPFEAPFRAEWILAAVKEAGFDDVVAPARHGLETVL
KVHDAGYLNFLETAWDRWKAAGYKGEAIATSFPVRRTSPRIPTDIEGQIGYYCNAAETAI
SPGTWEAALSSMASAIDGADLIAAGHKAAFSLCRPPGHHAGIDMFGGYCFINNAAVAAQR
LLDKGAKKIAILDVDFHHGNGTQDIFYERGDVFFASLHGDPAEAFPHFLGYAEETGKGAG
AGTTANYPMGRGTPYSVWGEALTDSLKRIAAFGAEAIVVSLGVDTFEQDPISFFKLTSPD
YITMGRTIAASGVPLLVVMEGGYGVPEIGLNVANVLKGVAG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50438388
NameBDBM50438388
Synonyms:CHEMBL2414002
TypeSmall organic molecule
Emp. Form.C11H24N2O2
Mol. Mass.216.3205
SMILESCOCC(=O)CCCCCNCCCN
Structure
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n/a