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TargetDeoxycytidine kinase
LigandBDBM50440165
Substrate/Competitorn/a
Meas. Tech.ChEMBL_981695
IC50 1760±n/a nM
Citation Murphy, JMArmijo, ALNomme, JLee, CHSmith, QALi, ZCampbell, DOLiao, HINathanson, DAAustin, WRLee, JTDarvish, RWei, LWang, JSu, YDamoiseaux, RSadeghi, SPhelps, MEHerschman, HRCzernin, JAlexandrova, ANJung, MELavie, ARadu, CG Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. J Med Chem56:6696-708 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Deoxycytidine kinase
Name:Deoxycytidine kinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:30361.42
Organism:Mus musculus
Description:ChEMBL_981695
Residue:260
Sequence:
MATPPKRFCPSPSTSSEGTRIKKISIEGNIAAGKSTFVNILKQASEDWEVVPEPVARWCN
VQSTQEEFEELTTSQKSGGNVLQMMYEKPERWSFTFQSYACLSRIRAQLASLNGKLKDAE
KPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFGQSLELDGIIYLRA
TPEKCLNRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTSFDYLQEVPVLTLDVNE
DFKDKHESLVEKVKEFLSTL
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  Blast E-value cutoff:
BDBM50440165
NameBDBM50440165
Synonyms:CHEMBL2424679
TypeSmall organic molecule
Emp. Form.C15H14BrN5OS2
Mol. Mass.424.339
SMILESCOc1ccc(Br)cc1-c1nc(CSc2nc(N)cc(N)n2)cs1
Structure
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n/a