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TargetPeptidyl-prolyl cis-trans isomerase A
LigandBDBM50440299
Substrate/Competitorn/a
Meas. Tech.ChEMBL_982571
Ki 12±n/a nM
Citation Malesevic, MGutknecht, DPrell, EKlein, CSchumann, MNowak, RASimon, JCSchiene-Fischer, CSaalbach, A Anti-inflammatory effects of extracellular cyclosporins are exclusively mediated by CD147. J Med Chem56:7302-11 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase A
Name:Peptidyl-prolyl cis-trans isomerase A
Synonyms:CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIase A | Rotamase A
Type:Protein
Mol. Mass.:18015.32
Organism:Homo sapiens (Human)
Description:P62937
Residue:165
Sequence:
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50440299
NameBDBM50440299
Synonyms:CHEMBL2424823
TypeSmall organic molecule
Emp. Form.C67H113N13O12
Mol. Mass.1292.694
SMILESCC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)Cc2nc3ccc(C)cc3[nH]2)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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