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Target
Beta-1 adrenergic receptor
Ligand
BDBM50442754
Substrate
n/a
Meas. Tech.
ChEMBL_989362 (CHEMBL2443397)
Ki
490±n/a nM
Citation
 Banerjee, A; Maschauer, S; Hübner, H; Gmeiner, P; Prante, O Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers. Bioorg Med Chem Lett 23:6079-82 (2013) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | ADRB1_PIG
Type:
PROTEIN
Mol. Mass.:
50109.86
Organism:
Sus scrofa
Description:
ChEMBL_989362
Residue:
468
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVPASPPASLLTPASEGSVQLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRAARALVCTVWAISALVSFLPILMHWWRDKGAEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGSPARPPSPAPSPGSPLPAAAAAAPVANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRVARGSCAAAGDGPRASGCLAVARPPPSPGAASDDDDDEEDVGAAPPAPLLEPWAGYNGGAARDSDSSLDERTPGGRASESKV
  
Inhibitor
Name:
BDBM50442754
Synonyms:
CHEMBL2443002
Type:
Small organic molecule
Emp. Form.:
C20H28FN5O5
Mol. Mass.:
437.4652
SMILES:
COc1ccccc1N1CCN(Cc2cn(nn2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2F)CC1 |r|
Structure:
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