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TargetKiSS-1 receptor
LigandBDBM50442961
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1276485
Ki 0.100000±n/a nM
Citation Asami, TNishizawa, NMatsui, HNishibori, KIshibashi, YHorikoshi, YNakayama, MMatsumoto, STarui, NYamaguchi, MMatsumoto, HOhtaki, TKitada, C Design, synthesis, and biological evaluation of novel investigational nonapeptide KISS1R agonists with testosterone-suppressive activity. J Med Chem56:8298-307 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
KiSS-1 receptor
Name:KiSS-1 receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:42915.37
Organism:Rattus norvegicus
Description:ChEMBL_1448383
Residue:396
Sequence:
MAAEATLGPNVSWWAPSNASGCPGCGVNASDGPGSAPRPLDAWLVPLFFAALMLLGLVGN
SLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVLGDFMCKFVNY
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSAPVLAL
HRLSPGPHTYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGRAAVRPAP
TDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRSYA
AYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCGPQRQRRPHASAHSDRAAPH
SVPHSRAAHPVRVRTPEPGNPVRRSPSVQDEHTAPL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50442961
NameBDBM50442961
Synonyms:CHEMBL3086284
TypeSmall organic molecule
Emp. Form.C56H76N16O12
Mol. Mass.1165.3026
SMILESCNC(N)=NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc1ccncc1)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r,w:4.4|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a