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TargetKallikrein 5
LigandBDBM50444602
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1282444
Ki 100000±n/a nM
Citation Tan, XBertonati, CQin, LFurio, LEl Amri, CHovnanian, AReboud-Ravaux, MVilloutreix, BO Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins. Eur J Med Chem70:661-8 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kallikrein 5
Name:Kallikrein 5
Synonyms:KLK-L2 | Kallikrein-5 | Kallikrein-like protein 2 | Stratum corneum tryptic enzyme
Type:PROTEIN
Mol. Mass.:32031.75
Organism:Homo sapiens (Human)
Description:ChEMBL_1282456
Residue:293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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  Blast E-value cutoff:
BDBM50444602
NameBDBM50444602
Synonyms:CHEMBL3099874
TypeSmall organic molecule
Emp. Form.C18H16N2O4
Mol. Mass.324.3306
SMILESCOc1ccc(NC(=O)C(=C/c2ccc(O)c(OC)c2)\C#N)cc1
Structure
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n/a