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Target
D(2) dopamine receptor
Ligand
BDBM50273465
Substrate
n/a
Meas. Tech.
ChEMBL_1282321 (CHEMBL3100268)
EC50
0.170000±n/a nM
Citation
 Risgaard, R; Jensen, M; Jørgensen, M; Bang-Andersen, B; Christoffersen, CT; Jensen, KG; Kristensen, JL; Püschl, A Synthesis and SAR study of a novel series of dopamine receptor agonists. Bioorg Med Chem 22:381-92 (2013) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50273465
Synonyms:
(+/-)-trans-1-Propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol | CHEMBL3098131 | CHEMBL455497
Type:
Small organic molecule
Emp. Form.:
C16H23NO
Mol. Mass.:
245.3599
SMILES:
CCCN1CCC[C@@H]2Cc3c(O)cccc3C[C@@H]12 |r|
Structure:
Search PDB for entries with ligand similarity: