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Target
Serine/threonine-protein kinase Nek6
Ligand
BDBM50445472
Substrate
n/a
Meas. Tech.
ChEMBL_1284299 (CHEMBL3108320)
IC50
>30000±n/a nM
Citation
 El Amrani, M; Lai, D; Debbab, A; Aly, AH; Siems, K; Seidel, C; Schnekenburger, M; Gaigneaux, A; Diederich, M; Feger, D; Lin, W; Proksch, P Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum. J Nat Prod 77:49-56 (2014) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase Nek6
Synonyms:
NEK kinase | NEK6 | NEK6_HUMAN
Type:
PROTEIN
Mol. Mass.:
35724.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1446777
Residue:
313
Sequence:
MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMHIWMSST
  
Inhibitor
Name:
BDBM50445472
Synonyms:
CHEMBL3104852
Type:
Small organic molecule
Emp. Form.:
C10H10O6
Mol. Mass.:
226.1828
SMILES:
COC1OC(=O)c2c1c(C)c(O)c(O)c2O
Structure:
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