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Target
von Hippel-Lindau disease tumor suppressor
Ligand
BDBM50446137
Substrate
n/a
Meas. Tech.
ChEMBL_1288131 (CHEMBL3110591)
Kd
36000±n/a nM
Citation
 Dias, DM; Van Molle, I; Baud, MG; Galdeano, C; Geraldes, CF; Ciulli, A Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? ACS Med Chem Lett 5:23-28 (2014) [PubMed]  Article 
Target
Name:
von Hippel-Lindau disease tumor suppressor
Synonyms:
Protein G7 | VHL | VHL_HUMAN | Von Hippel-Lindau disease tumor suppressor | Von Hippel-Lindau disease tumor suppressor protein (VBC) | pVHL
Type:
Protein
Mol. Mass.:
24136.87
Organism:
Homo sapiens (Human)
Description:
P40337
Residue:
213
Sequence:
MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD
  
Inhibitor
Name:
BDBM50446137
Synonyms:
CHEMBL3108880
Type:
Small organic molecule
Emp. Form.:
C18H21N3O3S
Mol. Mass.:
359.443
SMILES:
CC(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r|
Structure:
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