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Target
Arginase
Ligand
BDBM50446572
Substrate
n/a
Meas. Tech.
ChEMBL_1286565 (CHEMBL3110798)
IC50
35100±n/a nM
Citation
 de Sousa, LR; Ramalho, SD; Burger, MC; Nebo, L; Fernandes, JB; da Silva, MF; Iemma, MR; Corrêa, CJ; de Souza, DH; Lima, MI; Vieira, PC Isolation of arginase inhibitors from the bioactivity-guided fractionation of Byrsonima coccolobifolia leaves and stems. J Nat Prod 77:392-6 (2014) [PubMed]  Article 
Target
Name:
Arginase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36149.67
Organism:
Leishmania amazonensis
Description:
ChEMBL_107995
Residue:
329
Sequence:
MEHVQQYKFYKEKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISDGRAIARCMMGETLLYTPHTSSKL
  
Inhibitor
Name:
BDBM50446572
Synonyms:
CHEMBL3109441
Type:
Small organic molecule
Emp. Form.:
C21H22O10
Mol. Mass.:
434.3934
SMILES:
C[C@@H]1O[C@@H](O[C@H]2[C@@H](Oc3cc(O)cc(O)c3C2=O)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |r|
Structure:
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