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TargetAmiloride-sensitive amine oxidase [copper-containing]
LigandBDBM50446737
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1288377
IC50>1000000±n/a nM
Citation Lucchesini, FPocci, MAlfei, SBertini, VBuffoni, F Synthesis of 2,6-disubstituted benzylamine derivatives as reversible selective inhibitors of copper amine oxidases. Bioorg Med Chem22:1558-67 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amiloride-sensitive amine oxidase [copper-containing]
Name:Amiloride-sensitive amine oxidase [copper-containing]
Synonyms:ABP1 | AOC1 | Amiloride-binding protein 1 | Amine oxidase copper domain-containing protein 1 | DAO | Histaminase | PK-DAO
Type:PROTEIN
Mol. Mass.:85480.30
Organism:Sus scrofa
Description:ChEMBL_107996
Residue:755
Sequence:
MGRGTLALGWAGAALLLLQMLAAAERSPRTPGGKAGVFADLSAQELKAVHSFLWSQKELK
LEPSGTLTMAKNSVFLIEMLLPKKQHVLKFLDKGHRRPVREARAVIFFGAQEQPNVTEFA
VGPLPTPRYMRDLPPRPGHQVSWASRPISKAEYALLSHKLQEATQPLRQFFRRTTGSSFG
DCHEQCLTFTDVAPRGLASGQRRTWFILQRQMPGYFLHPTGLELLVDHGSTNAQDWTVEQ
VWYNGKFYRSPEELAQKYNDGEVDVVILEDPLAKGKDGESLPEPALFSFYQPRGDFAVTM
HGPHVVQPQGPRYSLEGNRVMYGGWSFAFRLRSSSGLQILDVHFGGERIAYEVSVQEAVA
LYGGHTPAGMQTKYIDVGWGLGSVTHELAPDIDCPETATFLDALHHYDADGPVLYPRALC
LFEMPTGVPLRRHFNSNFSGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEA
KMHATGYVHATFYTPEGLRYGTRLHTHLIGNMHTHLVNYRVDLDVAGTTNSFQTLQMELE
NITNPWSPRHRLVQPTLKQTRYSRERQAAFRFGQPLPKYLLITSPKENPWGHTRSYRLQL
HSMADQVLPPGWQEERAVTWARYPLAVTRYRESELSSSSIYNQNDPWDPPVVFEEFLRNN
ENIEDEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPALASRDLVVVW
PLENGSTYAQRWIPEEDQSCLKPPPFSYNGSYRPV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50446737
NameBDBM50446737
Synonyms:CHEMBL3114417
TypeSmall organic molecule
Emp. Form.C11H17NO2
Mol. Mass.195.2582
SMILESCOCc1cccc(COC)c1CN
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a