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TargetAlpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
LigandBDBM50447992
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1288745
IC50 230000±n/a nM
Citation Veleti, SKLindenberger, JJRonning, DRSucheck, SJ Synthesis of a C-phosphonate mimic of maltose-1-phosphate and inhibition studies on Mycobacterium tuberculosis GlgE. Bioorg Med Chem22:1404-11 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
Name:Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
Synonyms:(1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase | GMPMT | glgE
Type:PROTEIN
Mol. Mass.:78625.37
Organism:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:ChEMBL_108025
Residue:701
Sequence:
MSGRAIGTETEWWVPGRVEIDDVAPVVSCGVYPAKAVVGEVVPVSAAVWREGHEAVAATL
VVRYLGVRYPHLTDRPRARVLPTPSEPQQRVKPLLIPMTSGQEPFVFHGQFTPDRVGLWT
FRVDGWGDPIHTWRHGLIAKLDAGQGETELSNDLLVGAVLLERAATGVPRGLRDPLLAAA
AALRTPGDPVTRTALALTPEIEELLADYPLRDLVTRGEQFGVWVDRPLARFGAWYEMFPR
STGGWDDDGNPVHGTFATAAAELPRIAGMGFDVVYLPPIHPIGKVHRKGRNNSPTAAPTD
VGSPWAIGSDEGGHDTVHPSLGTIDDFDDFVSAARDLGMEVALDLALQCAPDHPWAREHR
QWFTELPDGTIAYAENPPKKYQDIYPLNFDNDPEGLYDEVLRVVQHWVNHGVKFFRVDNP
HTKPPNFWAWLIAQVKTVDPDVLFLSEAFTPPARQYGLAKLGFTQSYSYFTWRTTKWELT
EFGNQIAELADYRRPNLFVNTPDILHAVLQHNGPGMFAIRAVLAATMSPAWGMYCGYELF
EHRAVREGSEEYLDSEKYELRPRDFASALDQGRSLQPFITRLNIIRRLHPAFQQLRTIHF
HHVDNDALLAYSKFDPATGDCVLVVVTLNAFGPEEATLWLDMAALGMEDYDRFWVRDEIT
GEEYQWGQANYIRIDPARAVAHIINMPAVPYESRNTLLRRR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50447992
NameBDBM50447992
Synonyms:CHEMBL3115199
TypeSmall organic molecule
Emp. Form.C13H25O13P
Mol. Mass.420.3036
SMILESOC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](CP(O)(O)=O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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