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Target
N-arachidonyl glycine receptor
Ligand
BDBM50448076
Substrate
n/a
Meas. Tech.
ChEMBL_1292267 (CHEMBL3124698)
IC50
13400±n/a nM
Citation
 Harms, H; Rempel, V; Kehraus, S; Kaiser, M; Hufendiek, P; Müller, CE; König, GM Indoloditerpenes from a marine-derived fungal strain of Dichotomomyces cejpii with antagonistic activity at GPR18 and cannabinoid receptors. J Nat Prod 77:673-7 (2014) [PubMed]  Article 
Target
Name:
N-arachidonyl glycine receptor
Synonyms:
G-protein coupled receptor 18 | GPCRW | GPR18 | GPR18_HUMAN | NAGly receptor
Type:
PROTEIN
Mol. Mass.:
38150.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107601
Residue:
331
Sequence:
MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
  
Inhibitor
Name:
BDBM50448076
Synonyms:
CHEMBL3120632
Type:
Small organic molecule
Emp. Form.:
C29H41NO2
Mol. Mass.:
435.6413
SMILES:
COC(C)(C)\C=C\C[C@]1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C |r|
Structure:
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