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Target
Deoxyribonuclease-1
Ligand
BDBM50448688
Substrate
n/a
Meas. Tech.
ChEMBL_1297301 (CHEMBL3132087)
IC50
>200000±n/a nM
Citation
 Mizushina, Y; Suzuki-Fukudome, H; Takeuchi, T; Takemoto, K; Kuriyama, I; Yoshida, H; Kamisuki, S; Sugawara, F Formosusin A, a novel specific inhibitor of mammalian DNA polymeraseß from the fungus Paecilomyces formosus. Bioorg Med Chem 22:1070-6 (2014) [PubMed]  Article 
Target
Name:
Deoxyribonuclease-1
Synonyms:
DNAS1_BOVIN | DNASE1 | DNL1
Type:
PROTEIN
Mol. Mass.:
31341.11
Organism:
Bos taurus
Description:
ChEMBL_1297301
Residue:
282
Sequence:
MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
  
Inhibitor
Name:
BDBM50448688
Synonyms:
Pecilocin | Variotin
Type:
Small organic molecule
Emp. Form.:
C17H25NO3
Mol. Mass.:
291.3853
SMILES:
CCCC[C@@H](O)\C=C(/C)\C=C\C=C\C(=O)N1CCCC1=O |r|
Structure:
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