Reaction Details Report a problem with these data
Target
NADH-ubiquinone oxidoreductase chain 1
Ligand
BDBM50004703
Substrate
n/a
Meas. Tech.
ChEMBL_915023 (CHEMBL3059591)
IC50
1.5±n/a nM
Citation
  TBA Tetrahedron 60:10651-10657 (2004)    Article 
Target
Name:
NADH-ubiquinone oxidoreductase chain 1
Synonyms:
MT-ND1 | MTND1 | NADH Oxidase | NADH-ubiquinone oxidoreductase | NADH-ubiquinone oxidoreductase chain 1 | NADH1 | ND1 | NU1M_BOVIN
Type:
Protein
Mol. Mass.:
35672.63
Organism:
Bos taurus (Bovine)
Description:
P03887
Residue:
318
Sequence:
MFMINILMLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEPLRPATSSASMFILAPIMALGLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLITTQEQMWLILPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYANIIMMNIFTAILFLGTSHNPHMPELYTINFTIKSLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSLPILTSGIPPQT
  
Inhibitor
Name:
BDBM50004703
Synonyms:
Corossoline
Type:
Small organic molecule
Emp. Form.:
C35H64O6
Mol. Mass.:
580.8791
SMILES:
[H][C@@]1(CC[C@@]([H])(O1)[C@H](O)CCCC[C@H](O)CCCCCCCC1=C[C@H](C)OC1=O)[C@H](O)CCCCCCCCCCCC |r,t:23|
Structure:
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