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Target
Acetolactate synthase 2, chloroplastic
Ligand
BDBM50004707
Substrate
n/a
Meas. Tech.
ChEMBL_916416 (CHEMBL3082457)
IC50
14700±n/a nM
Citation
 Namgoong, SK; Lee, HJ; Kim, YS; Shin, JH; Che, JK; Jang, DY; Kim, GS; Yoo, JW; Kang, MK; Kil, MW; Choi, JD; Chang, SI Synthesis of the quinoline-linked triazolopyrimidine analogues and their interactions with the recombinant tobacco acetolactate synthase. Biochem Biophys Res Commun 258:797-801 (1999) [PubMed]  Article 
Target
Name:
Acetolactate synthase 2, chloroplastic
Synonyms:
ALS SURB | Acetolactate synthase | ILVB2_TOBAC
Type:
PROTEIN
Mol. Mass.:
72423.23
Organism:
Nicotiana tabacum
Description:
ChEMBL_106559
Residue:
664
Sequence:
MAAAAAAPSPSFSKTLSSSSSKSSTLLPRSTFPFPHHPHKTTPPPLHLTPTHIHSQRRRFTISNVISTTQKVSETQKAETFVSRFAPDEPRKGSDVLVEALEREGVTDVFAYPGGASMEIHQALTRSSIIRNVLPRHEQGGVFAAEGYARATGFPGVCIATSGPGATNLVSGLADALLDSVPIVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVVREAFFLARSGRPGPVLIDVPKDIQQQLVIPDWDQPMRLPGYMSRLPKLPNEMLLEQIVRLISESKKPVLYVGGGCSQSSEELRRFVELTGIPVASTLMGLGAFPTGDELSLSMLGMHGTVYANYAVDSSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKQPHVSICADIKLALQGLNSILESKEGKLKLDFSAWRQELTVQKVKYPLNFKTFGDAIPPQYAIQVLDELTNGSAIISTGVGQHQMWAAQYYKYRKPRQWLTSGGLGAMGFGLPAAIGAAVGRPDEVVVDIDGDGSFIMNVQELATIKVENLPVKIMLLNNQHLGMVVQWEDRFYKANRAHTYLGNPSNEAEIFPNMLKFAEACGVPAARVTHRDDLRAAIQKMLDTPGPYLLDVIVPHQEHVLPMIPSGGAFKDVITEGDGRSSY
  
Inhibitor
Name:
BDBM50004707
Synonyms:
CHEMBL2269035
Type:
Small organic molecule
Emp. Form.:
C16H13FN6O2S
Mol. Mass.:
372.377
SMILES:
Cc1cc(C)n2nc(nc2n1)S(=O)(=O)Nc1c(F)ccc2cccnc12
Structure:
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