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Target
Thymidine kinase, cytosolic
Ligand
BDBM50000969
Substrate
n/a
Meas. Tech.
ChEMBL_1333876 (CHEMBL3231765)
Ki
72000±n/a nM
Citation
 Hampton, A; Kappler, F; Chawla, RR Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase. J Med Chem 22:621-31 (1979) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_CRIGR | TK1
Type:
PROTEIN
Mol. Mass.:
25628.94
Organism:
Cricetulus griseus
Description:
ChEMBL_108265
Residue:
234
Sequence:
MNYINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQNKCLVIKYAKDTRYSSSFSTHDRNTMDALPACLLRDVAQEALGAAVIGIDEGQFFPDIVEFCEVMANAGKTVIVAALDGTFQRKAFGSILNLVPLAESVVKLTAVCMECFREAAYTKRLGLEKEVEVIGGADKYHSVCRVCYFKKSSVQPAGPDNKENCPVLGQPGEASAVRKLFAPQQVLQHNSTN
  
Inhibitor
Name:
BDBM50000969
Synonyms:
CHEMBL3143490
Type:
Small organic molecule
Emp. Form.:
C15H24N2O5
Mol. Mass.:
312.3615
SMILES:
CCCCCn1c(=O)c(C)cn([C@H]2C[C@H](O)[C@@H](CO)O2)c1=O |r|
Structure:
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