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Target
Thymidine kinase, cytosolic
Ligand
BDBM50000971
Substrate
n/a
Meas. Tech.
ChEMBL_1333876 (CHEMBL3231765)
Ki
160000±n/a nM
Citation
 Hampton, A; Kappler, F; Chawla, RR Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase. J Med Chem 22:621-31 (1979) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_CRIGR | TK1
Type:
PROTEIN
Mol. Mass.:
25628.94
Organism:
Cricetulus griseus
Description:
ChEMBL_108265
Residue:
234
Sequence:
MNYINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQNKCLVIKYAKDTRYSSSFSTHDRNTMDALPACLLRDVAQEALGAAVIGIDEGQFFPDIVEFCEVMANAGKTVIVAALDGTFQRKAFGSILNLVPLAESVVKLTAVCMECFREAAYTKRLGLEKEVEVIGGADKYHSVCRVCYFKKSSVQPAGPDNKENCPVLGQPGEASAVRKLFAPQQVLQHNSTN
  
Inhibitor
Name:
BDBM50000971
Synonyms:
CHEMBL3229794
Type:
Small organic molecule
Emp. Form.:
C14H21N3O6
Mol. Mass.:
327.333
SMILES:
[H][C@@]1(O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=O)C(O)CNC(=O)CC |r|
Structure:
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