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TargetNeuronal acetylcholine receptor subunit beta-2
LigandBDBM50006632
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1335312
IC50 580±n/a nM
Citation Crestey, FJensen, AABorch, MAndreasen, JTAndersen, JBalle, TKristensen, JL Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists. J Med Chem56:9673-82 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neuronal acetylcholine receptor subunit beta-2
Name:Neuronal acetylcholine receptor subunit beta-2
Synonyms:Chrnb2
Type:PROTEIN
Mol. Mass.:57114.19
Organism:Mus musculus
Description:ChEMBL_108396
Residue:501
Sequence:
MARCSNSMALLFSFGLLWLCSGVLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQL
MVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLY
NNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDR
TEIDLVLKSDVASLDDFTPSGEWDIIALPGRRNENPDDSTYVDITYDFIIRRKPLFYTIN
LIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKY
LMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQR
LRLRRRQREREGAGTLFFREGPAADPCTCFVNPASMQGLAGAFQAEPAAAGLGRSMGPCS
CGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQP
LFQNYTATTFLHSDHSAPSSK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50006632
NameBDBM50006632
Synonyms:CHEMBL3235508
TypeSmall organic molecule
Emp. Form.C16H22BrNO2
Mol. Mass.340.255
SMILESBr.[H][C@]12CCN3CCc4cc(O)c(O)cc4[C@]13CCCC2 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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