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Target
Cytidine deaminase
Ligand
BDBM50007025
Substrate
n/a
Meas. Tech.
ChEMBL_1337494 (CHEMBL3241962)
IC50
340±n/a nM
Citation
 Ferraris, D; Duvall, B; Delahanty, G; Mistry, B; Alt, J; Rojas, C; Rowbottom, C; Sanders, K; Schuck, E; Huang, KC; Redkar, S; Slusher, BB; Tsukamoto, T Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem 57:2582-8 (2014) [PubMed]  Article 
Target
Name:
Cytidine deaminase
Synonyms:
CDA | CDD | CDD_HUMAN | Cytidine deaminase | Cytidine deaminase (CDA)
Type:
Ezyme
Mol. Mass.:
16185.04
Organism:
Homo sapiens (Human)
Description:
P32320
Residue:
146
Sequence:
MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
  
Inhibitor
Name:
BDBM50007025
Synonyms:
TETRAHYDROURIDINE
Type:
Small organic molecule
Emp. Form.:
C9H16N2O6
Mol. Mass.:
248.2331
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CC[C@@H](O)NC1=O |r|
Structure:
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