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Target
Proteasome subunit beta type-5
Ligand
BDBM50434767
Substrate
n/a
Meas. Tech.
ChEMBL_1334922 (CHEMBL3239238)
Ki
800±n/a nM
Citation
 Scarbaci, K; Troiano, V; Micale, N; Ettari, R; Tamborini, L; Di Giovanni, C; Cerchia, C; Grasso, S; Novellino, E; Schirmeister, T; Lavecchia, A; Zappalą, M Identification of a new series of amides as non-covalent proteasome inhibitors. Eur J Med Chem 76:1-9 (2014) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-5
Synonyms:
20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X
Type:
Protein
Mol. Mass.:
28480.96
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
263
Sequence:
MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
  
Inhibitor
Name:
BDBM50434767
Synonyms:
CHEMBL2385811
Type:
Small organic molecule
Emp. Form.:
C16H28BN3O4
Mol. Mass.:
337.222
SMILES:
CCN(CC)c1ccn(CC(=O)N[C@@H](CC(C)C)B(O)O)c(=O)c1 |r|
Structure:
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