Reaction Details Report a problem with these data
Target
Fe(3+)-Zn(2+) purple acid phosphatase
Ligand
BDBM50008082
Substrate
n/a
Meas. Tech.
ChEMBL_1337988 (CHEMBL3241395)
IC50
80000±n/a nM
Citation
 McGeary, RP; Schenk, G; Guddat, LW The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-ß-lactamases and arginases. Eur J Med Chem 76:132-44 (2014) [PubMed]  Article 
Target
Name:
Fe(3+)-Zn(2+) purple acid phosphatase
Synonyms:
Iron(III)-zinc(II) purple acid phosphatase | PAP | PPAF_PHAVU
Type:
PROTEIN
Mol. Mass.:
52875.57
Organism:
Phaseolus vulgaris
Description:
ChEMBL_560427
Residue:
459
Sequence:
MGVVKGLLALALVLNVVVVSNGGKSSNFVRKTNKNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST
  
Inhibitor
Name:
BDBM50008082
Synonyms:
CHEMBL1794623
Type:
Small organic molecule
Emp. Form.:
CH5O3PS
Mol. Mass.:
128.087
SMILES:
OP(O)(=O)CS
Structure:
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